Table 2.

Patients’ follow-up data

Case No.	Actual status	Period of follow-up, yr	Year of PAH diagnosis	Initial specific therapy	Last visit specific therapy	Initial 6MWT (m)	Final 6MWT (m)	Variation on NYHA FC
1	Dead (cause: heart failure)	2.8	1998	Epoprostenol	Epoprostenol	211	463	0
2	Alive	11.3	2001	Treprostinil	Sildenafil	NA	669	-1
3	Alive	10.8	2001	Sildenafil	Sildenafil + Ambrisentan	512	630	-1
4	Alive	9.9	2002	Sildenafil	Sildenafil + Ambrisentan + Iloprost	516	570	-2
5	Alive	11.3	2001	Treprostinil	Sildenafil	313	414	0
6	Dead (cause: liver disease)	0.3	2005	Sildenafil	Sildenafil	400	NA	NA
7	Alive	7.0	2005	Ambrisentan	Ambrisentan + Sildenafil	435	473	0
8	Missing	3.9	2006	Sildenafil	Sildenafil	300	511	-2
9	Alive	5.3	2006	Sildenafil	Sildenafil	455	546	0
10	Alive	4.5	2007	Sildenafil	Tadalafil	650	703	0
11	Alive	8.5	2003	Treprostinil	Tadalafil	510	570	-2
12	Alive	8.8	2003	Iloprost	Ambrisentan	NA	450	-1
13	Alive	11.8	2000	Treprostinil	Bosentan	327	489	-1
14	Missing	0.4	2005	Sildenafil	Sildenafil	500	NA	0
15	Alive	3.5	2008	Sildenafil + Bosentan	Sildenafil + Bosentan + Iloprost	350	420	0
16	Alive	1.6	2010	Tadalafil	Tadalafil	525	570	0
17	Alive	1.4	2011	Ambrisentan	Ambrisentan	439	423	0
18	Alive	0.5	2011	Sildenafil	Sildenafil	537	600	0

6MWT: 6 min walk test; NYHA FC: New York heart association functional class; NA: Not accessible; PAH: Pulmonary arterial hypertension.