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(A,B) Replication of differentially methylated genes in an independent case-control cohort of 118 depressed and 236 control unrelated females. The plot shows significantly increased methylation levels of the ZBTB20 DMR region in individuals with MDD. (C) Case versus control RPM counts for the DMR of ZBTB20 in 50 MZ twin pairs discordant for MDD.
