Table 1.
Meta-analysis of 54 UK and 46 Australian blood samples using a fixed effects model approach
| Chromosome | Start | Stop | P- value | Adjusted P- value | Gene start | Gene stop | Gene name | Distance | Description |
|---|---|---|---|---|---|---|---|---|---|
| Chr5 |
63738001 |
63738501 |
1.75E-11 |
0.00019 |
63802451 |
63908121 |
RGS7BP |
63950 |
Regulator of G-protein signaling 7 binding protein |
| Chr3 |
114618751 |
114619251 |
4.34E-11 |
0.00048 |
114056946 |
114866127 |
ZBTB20
|
- |
Zinc finger and BTB domain containing 20 |
| Chr1 |
120633001 |
120633501 |
1.12E-10 |
0.00125 |
120454175 |
120612317 |
NOTCH2 |
20684 |
Notch homolog 2 (Drosophila) |
| Chr9 |
84715501 |
84716001 |
1.47E-10 |
0.00164 |
84603686 |
84610171 |
FLJ46321 |
105330 |
FAM75-like protein FLJ46321 |
| Chr1 |
9845751 |
9846251 |
1.58E-10 |
0.00176 |
9789078 |
9884550 |
CLSTN1
|
- |
Calsyntenin 1 |
| Chr9 |
88306501 |
88307001 |
2.02E-10 |
0.00225 |
88161453 |
88356944 |
AGTPBP1
|
- |
ATP/GTP binding protein 1 |
| Chr3 |
36140001 |
36140501 |
4.93E-10 |
0.00549 |
36422096 |
36589496 |
STAC |
281595 |
SH3 and cysteine rich domain |
| Chr7 |
17309251 |
17309751 |
1.35E-09 |
0.01503 |
17338275 |
17385775 |
AHR |
28524 |
Aryl hydrocarbon receptor |
| Chr1 |
166550001 |
166550501 |
1.56E-09 |
0.01737 |
166573152 |
166594473 |
FMO9P |
22651 |
Flavin containing monooxygenase 9 pseudogene |
| Chr3 |
66970001 |
66970501 |
1.69E-09 |
0.01881 |
67048726 |
67061632 |
KBTBD8 |
78225 |
Kelch repeat and BTB (POZ) domain |
| Chr12 |
132823251 |
132823751 |
2.30E-09 |
0.02560 |
132680916 |
132905905 |
GALNT9
|
- |
UDP-N-acetyl-alpha-D-galactosamine |
| Chr2 |
101764501 |
101765001 |
2.91E-09 |
0.03239 |
101623689 |
101767846 |
TBC1D8
|
- |
TBC1 domain family, member 8 |
| Chr12 |
57688251 |
57688751 |
3.37E-09 |
0.03752 |
57647547 |
57704246 |
R3HDM2
|
- |
R3H domain containing 2 |
| Chr2 |
221655001 |
221655501 |
3.42E-09 |
0.03807 |
222282746 |
222437010 |
EPHA4 |
627245 |
EPH receptor A4 |
| Chr4 |
182369251 |
182369751 |
3.63E-09 |
0.04041 |
181985242 |
182080302 |
LINC00290 |
288949 |
Long intergenic non-protein coding RNA 290 |
| Chr6 |
24236501 |
24237001 |
3.88E-09 |
0.04319 |
24171982 |
24358280 |
DCDC2
|
- |
Double cortin domain containing 2 |
| Chr4 |
15620251 |
15620751 |
4.30E-09 |
0.04787 |
15606006 |
15657035 |
FBXL5
|
- |
F-box and leucine-rich repeat protein 5 |
| Chr4 |
170932501 |
170933001 |
4.65E-09 |
0.05177 |
170907747 |
170947429 |
MFAP3L
|
- |
Microfibrillar-associated protein 3-like |
| Chr16 |
55912001 |
55912501 |
4.93E-09 |
0.05488 |
55880065 |
55989943 |
CES5A
|
- |
Carboxylesterase 5A |
| Chr12 |
126885001 |
126885501 |
5.67E-09 |
0.06312 |
126927026 |
126957331 |
LOC100128554 |
41525 |
Uncharacterized LOC100128554 |
| Chr10 |
22007501 |
22008001 |
6.22E-09 |
0.06924 |
21823100 |
22032559 |
MLLT10
|
- |
Myeloid/lymphoid leukemia |
| Chr1 |
172293751 |
172294251 |
6.57E-09 |
0.07314 |
171810620 |
172381857 |
DNM3
|
- |
Dynamin 3 |
| Chr1 | 75392751 | 75393251 | 6.61E-09 | 0.07358 | 75198861 | 75232360 | TYW3 | 160391 | tRNA-yW synthesizing protein 3 |
The nearest gene feature to a DMR is shown, DMRs occurring within a coding region are shown in bold. Bonferoni adjusted P-values with a significance <0.01 are also shown in bold.