Table 1.
AnyManEpa | ManEp | HypoEp | SubManEp | NoManEp | Comparis on among the 3 manic spectrum and no mania groups |
|
---|---|---|---|---|---|---|
Mean (SD) or N (%) |
Mean (SD) or N (%) |
Mean (SD) or N (%) |
Mean (SD) or N (%) |
Mean (SD) or N (%) |
||
(N=1,237) | (N=46) | (N=195) | (N=1,041) | (N=13,588) | p-value | |
Age at entry, years |
37.5 (17.1) | 33.8 (13.7)1 | 34.4(14.5)1 | 38.8 (17.8)1 | 49.6 (20.3) | <0.001 |
Age of death, years |
67.8 (16.8) | 69.8 (19.0) | 64.5 (16.6)1 | 68.8(16.8) | 78.2 (13.0) | <0.001 |
Caucasian | 688 (55.6) | 27 (58.7) | 123 (62.1)1,2 | 567 (54.6)1 | 9,608 (70.8) | <0.001 |
Female | 611 (49.4) | 23 (50.0)1 | 110 (56.4)1,2 | 507 (48.7)1 | 8,014 (59.0) | <0.001 |
Married | 405 (32.8) | 16 (34.8) | 51 (26.3)1,2 | 354 (34.0)1 | 6,509 (47.9) | <0.001 |
Education, years |
11.4 (3.2) | 11.3 (3.1) | 11.7 (2.9) | 11.3 (3.2) | 11.2 (3.4) | 0.162 |
Depressive symptoms |
5.3 (2.6) | 5.3 (2.6)1,2,3 | 6.0 (2.3)12 | 3.9 (2.4)1 | 1.4 (1.8) | <0.001 |
Hx Alcohol Abuse/Depen dence |
386 (31.4) | 17 (37.8)1 | 74 (38.1)1,2 | 307 (29.7)1 | 1,415 (10.5) | <0.001 |
Hx Non- Alcohol DrugaAbuse/Depen dence |
247 (20.1) | 13 (28.3)1 | 59 (30.6)1,2 | 179 (17.3)1 | 604 (4.5) | <0.001 |
Deceased during follow- up |
330 (27.1) | 6 (13.0)1,2 | 40 (20.5)1,2 | 307 (29.7)1 | 5,826 (42.9) | <0.001 |
significant (p<0.05) pairwise difference with the no lifetime manic spectrum episode (NoManEp) group
significant (p<0.05) pairwise difference with lifetime sub-threshold manic episode (SubManEp) group
significant (p<0.05) pairwise difference with lifetime hypomanic episode (HypoEp) group