Table 1.
Cytotoxic activity of recombinant parasporin-5 (PS5) protein against various cultured mammalian cells.
| Cell line | Origin | EC50 (μg/mL) |
|---|---|---|
| MOLT-4 | leukemic T cell, human | 0.075 |
| CACO-2 | colon cancer, human | 0.30 |
| Jurkat | leukemic T cell, human | 0.124 |
| A549 | lung cancer, human | 4.41 |
| HepG2 | hepatocyte cancer, human | 0.049 |
| TCS | uterus cervix cancer, human | 0.046 |
| HL60 | promyelocytic leukemia cell, human | 1.079 |
| K562 | myelogenous leukemia cell, human | 4.249 |
| U937 | DE-4 lymphoma cell, human | >10 |
| HeLa | uterus cervix cancer, human | 0.080 |
| COS7 | kidney cell, monkey | 0.045 |
| NIH3T3 | embryo cell, NIH Swiss mouse | 0.321 |
| Vero | kidney cell, monkey | 0.050 |
| CHO-K1 | ovary cell, chinese hamster | 0.571 |
| Sawano | uterus cancer, human | 0.065 |
| MRC-5 | normal embryonic lung fibroblast, human | 0.273 |
| UtSMC | normal uterus, human | 0.223 |
| HC | normal hepatocyte, human | >10 |