SBS reduces hepatic lipid levels in HFD-induced hepatic steatosis in rats. (A) Hepatic TG and TC levels in rats fed a normal diet (ND), high-fat diet (HFD), and high-fat diet supplemented with SBS. Significant decreases in the levels of hepatic triglyceride and total cholesterol were observed in the SBS-treated groups compared with HFD-induced obese rats. Values are expressed as mean ± SD. * p < 0.05, ** p < 0.01. (B) Representative histological section of H & E staining of liver prepared from rats fed ND, HFD, and HFD supplemented with SBS (magnification 200×, scale bar = 100 µm). The major histological change induced by HFD in rat liver was hepatocyte steatosis and ballooning.