Table 1.
Subject characteristics, body composition and serum lipids of normal-weight and obese black and white women.
| Subject characteristics | Black, n = 147 | White, n = 121 | p-values | ||||
|---|---|---|---|---|---|---|---|
| Normal-weight | Obese | Normal-weight | Obese | BMI Group | Ethnicity | Interaction | |
| n | 73 | 74 | 73 | 48 | - | - | - |
| Age, years | 24 ± 6 | 30 ± 8 | 28 ± 7 | 34 ± 9 | <0.001 | <0.001 | 0.969 |
| Body Composition a | |||||||
| Height, m | 1.61 ± 0.06 | 1.59 ± 0.06 | 1.67 ± 0.07 | 1.67 ± 0.07 | 0.009 | <0.001 | 0.350 |
| Weight, kg | 58 ± 6 | 91 ± 13 | 61 ± 6 | 97 ± 14 | <0.001 | 0.001 | 0.272 |
| BMI, kg/m2 | 22 ± 2 | 36 ± 5 | 21 ± 2 | 35 ± 4 | <0.001 | 0.005 | 0.596 |
| Fat Mass, kg | 17 ± 4 | 41 ± 9 | 17 ± 4 | 44 ± 9 | <0.001 | 0.190 | 0.045 |
| Body fat, % | 31 ± 5 | 45 ± 4 | 28 ± 5 | 45 ± 4 | <0.001 | 0.006 | 0.004 |
| Waist, cm | 74 ± 6 | 103 ± 12 | 77 ± 6 | 106 ± 10 | <0.001 | 0.004 | 0.972 |
| WHR | 0.75 ± 0.06 | 0.83 ± 0.08 | 0.78 ± 0.05 | 0.85 ± 0.06 | <0.001 | <0.001 | 0.426 |
| Metabolic Outcomes b | |||||||
| TAG, mmol/L | 0.50 (0.40–0.70) | 0.80 (0.60–1.04) | 0.80 (0.60–1.08) | 1.10 (0.78–1.50) | <0.001 | <0.001 | 0.339 |
| T-C, mmol/L | 3.8 (3.3–4.2) | 4.1 (3.6–4.5) | 4.5 (4.0–5.0) | 5.0 (4.4–5.7) | 0.031 | <0.001 | 0.357 |
| HDL-C, mmol/L | 1.5 (1.2–1.7) | 1.1 (1.0–1.3) | 1.8 (1.6–2.0) | 1.5 (1.3–1.6) | <0.001 | < 0.001 | 0.638 |
| LDL-C, mmol/L | 2.1 (1.6–2.5) | 2.5 (2.0–2.9) | 2.3 (1.9–2.7) | 2.9 (2.6–3.5) | <0.001 | < 0.001 | 0.215 |
| T-C:HDL–C ratio | 2.6 (2.2–3.1) | 3.5 (2.9–4.1) | 2.6 (2.2–2.8) | 3.5 (3.0–4.2) | <0.001 | 0.520 | 0.260 |
TAG, triglycerides; T-C, total cholesterol; HDL-C, high density lipoprotein cholesterol; LDL-C, low density lipoprotein cholesterol; T-C:HDL-C ratio, total cholesterol: high density lipoprotein cholesterol ratio; %E, percentage of total energy intake; a Body composition:Summarised as mean and SD. p-values are from age adjusted linear models of the interaction between BMI group and genotype on variable. p-values were calculated consecutively, from left to right, each adjusted for age and factors already tested; b Lipids: Summarised as median (interquartile range). Outcomes were log-transformed for modelling. p-values are from age adjusted linear models of the interaction between BMI group and genotype on variable. p-values were calculated consecutively, from left to right, each adjusted for age and factors already tested.