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. 2014 Jun 16;13:152. doi: 10.1186/1476-4598-13-152

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Copyright © 2014 Juengel et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Dose response analysis of Caki^parand Caki^res. (A) Growth efficacy of increasing concentrations of everolimus on Caki^par and Caki^res cell growth from 24 h to 72 h. *Indicates significant difference to controls, set to 100% (SD ≤ 16%, n = 6). IC₅₀-values of Caki^par and Caki^res cells were calculated from dose response analysis. (B) Cell cycle analysis of unsynchronized and synchronized Caki^par and Caki^res cells in subconfluent cell cultures. The cell phase is expressed as percentage of total cells. The figure shows one of five separate experiments.