Table 1. Characteristics of the study populations.
| First author | Year | Histology | Stage | N pts | Positive N | Positive rate | Method | HR estimation | Cut off | Results |
|---|---|---|---|---|---|---|---|---|---|---|
| Weiss | 2010 | SQCC | I-III | 155 | 15 | 9.68% | FISH | Survival curve | Copy number >4 | NS |
| Rebecca | 2012 | SQCC | I-IV | 226 | 37 | 16.37% | FISH | Survival curve | FGFR1/CEP8 ratio ≥2.2 | NS |
| Kim | 2012 | SQCC | I-III | 262 | 34 | 12.98% | FISH | HR | Copy number >9 | Poor prognosis |
| Sasaki | 2012 | NSCLC | I-IV | 100 | 32 | 32.00% | RT-PCR | Survival curve | Copy number >4 | NS |
| Tran | 2013 | NSCLC | I-IV | 264 | 37 | 14.02% | Dual-Colour ISH | survival curve | FGFR1/CEP8 ratio ≥2.0 | NS |
| Craddock | 2013 | SQCC | I-IV | 121 | 11 | 9.09% | FISH | HR | Copy number >5 | NS |
N pts, number of patients; HR, hazard ratio; NSCLC, non-small-cell lung cancer; SQCC, squamous cell lung cancer; FISH, fluorescence in situ hybridization; PCR, polymerase chain reaction; NS, non-significant.