Table 2. Univariate analysis of PFS of retreatment with pemetrexed.

	PFS	95% CI	P
Sex			0.07
Male	1.2	0.67-1.7
Female	2.1	0.6-3.9
Age			0.6
≥65	1.5	0.1-2.9
<65	1.5	1.1-1.9
PS			0.031
0-1	2.4	1.2-3.5
2	1.1	0.8-1.5
Retreatment in which line			0.77
Fourth-line	1.5	1.1-1.9
Further-line	1.5	0.9-2.1
Smoking history			0.11
Yes	1.2	0.4-2.2
No	2.1	1.1-3.5
Initial pemetrexed PFS			0.036
>6 months	2.2	1.9-4.5
≤6 months	1.1	0.6-2.1

PFS, progression-free survival.