Table 4.
Association of combined systolic and diastolic BP groups with outcomes
| Systolic BP and Diastolic BP Categorya | n | CVD | Mortality | Composite | |||
|---|---|---|---|---|---|---|---|
| HR (95% CI) | P Value | HR (95% CI) | P Value | HR (95% CI) | P Value | ||
| Low_Low | 324 | 1.19 (0.83 to 1.70) | 0.34 | 0.89 (0.59 to 1.35) | 0.58 | 1.13 (0.84 to 1.53) | 0.41 |
| Low_Mod | 325 | 1.13 (0.75 to 1.72) | 0.56 | 1.00 (0.63 to 1.58) | 1.00 | 1.14 (0.81 to 1.61) | 0.45 |
| Mod_Low | 298 | 1.57 (1.14 to 2.17) | 0.01 | 1.51 (1.08 to 2.11) | 0.02 | 1.56 (1.19 to 2.04) | 0.001 |
| Mod_Mod | 1034 | Reference | — | Reference | — | Reference | — |
| Mod_High | 128 | 0.62 (0.27 to 1.44) | 0.27 | 0.81 (0.37 to 1.78) | 0.60 | 0.77 (0.41 to 1.44) | 0.41 |
| High_Low | 124 | 1.82 (1.24 to 2.67) | 0.002 | 1.47 (0.97 to 2.24) | 0.07 | 1.65 (1.18 to 2.29) | 0.003 |
| High_Mod | 741 | 1.50 (1.16 to 1.95) | 0.002 | 1.02 (0.77 to 1.35) | 0.89 | 1.30 (1.04 to 1.62) | 0.02 |
| High_High | 494 | 1.65 (1.17 to 2.32) | 0.004 | 1.24 (0.86 to 1.79) | 0.25 | 1.48 (1.11 to 1.97) | 0.01 |
Models are adjusted for age, sex, race, diabetes, prior CVD, eGFR, treatment allocation, country of origin, smoking, LDL, HDL, triglycerides, ACR, BMI, donor type, graft vintage, BP medication use, and systolic/diastolic BP.
a
Systolic BP categories are as follows: low, <120 mmHg; moderate, 120–139 mmHg; and high, ≥140 mmHg. Diastolic BP categories are as follows: low, <70 mmHg; moderate, 70–89 mmHg; and high, ≥90 mmHg.