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The Ren1dCre mice express the Cre recombinase in the juxtoglomerular apparatus and in the collecting duct. Immunohistochemical localization of Cre recombinase in the renal cortex (ZT4). Strong nuclear Cre staining (black) is present in the arterioles of the juxtaglomerular apparatus (red arrows) and the collecting duct (blue arrows), which is evidenced by costaining with aquaporin-2 (AQP2) water channel (red).
