Table 2.
Echocardiographic parameters and eGFR at baseline and 1 year and changes over 1 year
| Variable | Baseline | 1 Year | Changes over 1 Year | P Value |
|---|---|---|---|---|
| eGFR (ml/min per 1.73 m2) | 30.9±15.4 | 28.5±17.0 | −2.0 (−5.0, 0.0) | <0.001 |
| LV mass index (g/m2) | 105±32 | 112±34 | 6.4 (0.6, 13.1) | <0.001 |
| LV volume index (ml/m2) | 42.8±11.1 | 43.9±11.8 | 0.9 (−1.5, 3.6) | 0.004 |
| LV ejection fraction (%) | 70.0±6.8 | 69.0±6.9 | −1.0 (−6.0, 3.0) | 0.02 |
| Midwall FS (%) | 17.7±2.3 | 17.4±2.6 | −0.3 (−1.9, 0.9) | 0.004 |
| LAVi (ml/m2) | 30.6±12.6 | 35.3±13.7 | 4.8 (2.1, 7.7) | <0.001 |
| E (cm/s) | 81.2±21.5 | 82.7±21.9 | 1.0 (−9.0, 12.0) | 0.2 |
| A (cm/s) | 87.2±22.3 | 88.8±24.3 | 1.0 (−7.0, 12.0) | 0.1 |
| E/A | 0.97±0.3 | 1.00±0.5 | 0 (−0.1, 0.1) | 0.4 |
| Sm (cm/s) | 9.0±1.9 | 8.4±2.0 | −0.5 (−1.5, 0.5) | <0.001 |
| Em (cm/s) | 9.7±2.8 | 9.0±2.6 | −0.5 (−1.5, 0.5) | <0.001 |
| Am (cm/s) | 11.6±2.3 | 11.3±2.3 | −0.5 (−1.5, 1.0) | 0.06 |
| E/Em | 9.0±3.4 | 9.7±3.8 | 0.7 (−0.5, 2.0) | <0.001 |
Continuous data are expressed as mean±SD. Changes over 1 year expressed as median (IQR). FS, fractional shortening; A, peak late transmitral flow velocity; E, peak early transmitral flow velocity; E/A, ratio of early to late transmitral flow velocity.