TABLE 5 .
SNP location | Gene locant: protein encoded | Gene start (NT) | Gene stop (NT) | CmVar001 |
CmVar001.1 |
CmVar002 |
CmVar003 |
CmVar004 |
|||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
NT change | AA change | NT change | AA change | NT change | AA change | NT change | AA change | NT change | AA change | ||||
58847 | TC_0052: major outer membrane protein, porin | 58653 | 59816 | C→A | G→C | C→A | G→C | ||||||
58899 | TC_0052: major outer membrane protein, porin | 58653 | 59816 | A→ | DEL | A→ | DEL | ||||||
58900 | TC_0052: major outer membrane protein, porin | 58653 | 59816 | A→ | DEL | A→ | DEL | ||||||
58901 | TC_0052: major outer membrane protein, porin | 58653 | 59816 | G→ | DEL | G→ | DEL | ||||||
58902 | TC_0052: major outer membrane protein, porin | 58653 | 59816 | C→ | DEL | C→ | DEL | ||||||
58903 | TC_0052: major outer membrane protein, porin | 58653 | 59816 | T→ | DEL | T→ | DEL | ||||||
59061 | TC_0052: major outer membrane protein, porin | 58653 | 59816 | T→ | DEL | T→ | DEL | T→ | DEL | ||||
59062 | TC_0052: major outer membrane protein, porin | 58653 | 59816 | G→ | DEL | G→ | DEL | G→ | DEL | ||||
59063 | TC_0052: major outer membrane protein, porin | 58653 | 59816 | T→ | DEL | T→ | DEL | T→ | DEL | ||||
187432 | TC_0155: 3′(2′),5′-bisphosphate nucleotidase, putative | 187163 | 188212 | G→A | H→Y | G→A | H→Y | G→A | H→Y | ||||
187984 | TC_0155: 3′(2′),5′-bisphosphate nucleotidase, putative | 187163 | 188212 | C→T | G→S | ||||||||
381736 | Intergenic: NA | NA | NA | T→A | NA→NA | ||||||||
473191 | TC_0412: conserved hypothetical protein | 472757 | 473854 | →A | FS | →A | FS | ||||||
473705 | TC_0412: conserved hypothetical protein | 472757 | 473854 | G→ | FS | G→ | FS | G→ | FS | ||||
798169 | TC_0668: conserved hypothetical protein | 797014 | 798240 | T→G | F→V | ||||||||
814976 | TC_0682: tetraacyldisaccharide 4′-kinase | 814899 | 816008 | C→A | V→L | C→A | V→L | C→A | V→L | ||||
1004276 | TC_0867: conserved hypothetical protein | 1002965 | 1004440 | T→C | S→P | T→C | S→P | T→C | S→P | T→C | S→P | ||
1062351 | Intergenic | NA | NA | C→A | NA→NA | C→A | NA→NA | C→A | NA→NA |
Mutations common to all variants are excluded (see Table S1 in the supplemental material for the entire list). Chlamydial variants are arranged from highest growth rate to lowest (left to right). Gross pathology results also followed this pattern. FS, frameshift; DEL, deletion; INS, insertion; NA, not applicable (intergenic); NT change, nucleotide change; AA change, amino acid change.