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. Author manuscript; available in PMC: 2014 Jun 27.
Published in final edited form as: Mol Cell Endocrinol. 2003 Dec 15;211(0):1–7. doi: 10.1016/j.mce.2003.09.021

Fig. 4.

Fig. 4

Normal early testis differentiation in Amh−/− embryos. (A, and B) Gonads from wild-type (A) and Amh −/− (B) 11.5 dpc XY embryos were cultured for 48 h with ROSA26 mesonephroi. Similar levels of mesonephric migration were observed in both samples. (C, and D) Immunostaining for laminin (green) and PECAM-1 (red) on 12.5 dpc wild-type (C) and Amh −/− (D) XY gonads. Amh mutant gonads displayed normal morphology and coelomic vessel formation (arrows). (E, and F) Whole mount in situ hybridization for Sox9 expression in 12.5 dpc wild-type (E) and Amh −/− (F) XY gonads. Sertoli cell differentiation appears normal in Amh mutants, as demonstrated by Sox9 expression. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)