Table 3.

 Sensitivity analyses: number of events and risk of in-hospital mortality in patients receiving different types of anesthesia. Values are risk ratios (95% confidence intervals) unless stated otherwise

Variables	General anesthesia	Regional anesthesia	General and regional anesthesia
Patients undergoing hip fracture surgery independently of surgical procedure timing:
No of patients	79 915	9079	6843
No of in-hospital deaths	1607	167	142
Risk of in-hospital death (%)	2.0	1.8	2.1
Unadjusted analysis	Ref	0.91 (0.78 to 1.07)	1.03 (0.87 to 1.23)
Adjusted analysis*	Ref	0.89 (0.76 to 1.05)	0.98 (0.82 to 1.16)
Fully adjusted analysis†	Ref	0.91 (0.77 to 1.08)	0.97 (0.82 to 1.17)
Patients with no recorded diagnosis of cancer at discharge:
No of patients	49 648	5565	3856
No of in-hospital deaths	1035	110	86
Risk of in-hospital death (%)	2.1	2.0	2.2
Unadjusted analysis	Ref	0.95 (0.78 to 1.16)	1.07 (0.86 to 1.34)
Adjusted analysis*	Ref	0.94 (0.77 to 1.14)	1.01 (0.81 to 1.27)
Fully adjusted analysis	Ref	0.93 (0.76 to 1.15)	0.97 (0.77 to 1.22)
Patients aged 75 years and older:
No of patients	45 709	5564	3753
No of in-hospital deaths	1154	126	96
Risk of in-hospital death (%)	2.5	2.3	2.6
Unadjusted analysis	Ref	0.89 (0.74 to 1.08)	1.01 (0.82 to 1.25)
Adjusted analysis*	Ref	0.94 (0.78 to 1.13)	0.99 (0.80 to 1.22)
Fully adjusted analysis	Ref	0.92 (0.76 to 1.12)	0.95 (0.77 to 1.18)

*Adjusted for age, sex, ethnicity, and calendar year.

†Includes all covariates noted in table 1 except for inpatient use of drugs and services before day of surgery.