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. Author manuscript; available in PMC: 2014 Dec 26.
Published in final edited form as: Cell Rep. 2013 Dec 12;5(6):1625–1638. doi: 10.1016/j.celrep.2013.11.025

Figure 3. PRMT4 regulates miR-223 expression.

Figure 3

(A). PRMT4 downregulation leads to upregulation of miR-223 expression. qRT-PCR data represents the mean ± SD of three independent experiments. *** p < 0.001 by Student's t test.

(B). Overexpression of miR-223 in HSPCs enhances myeloid differentiation. (Left) qRT-PCR data represents the mean ± SD of three independent experiments. ** p < 0.01 by Student's t test. (Right) Cells were plated in myeloid differentiation promoting culture and assayed for CD11b expression after 7 days.

(C). Overexpression of PRMT4 diminishes miR-223 expression. qRT-PCR data represents the mean ± SD of three independent experiments. *** p < 0.001 by Student's t test.

(D). Knock down of miR-223 in HSPCS slightly impairs myeloid differentiation. (Left) qRT-PCR data represents the mean ± SD of three independent experiments. * p < 0.05 by Student's t test. (Right) Cells were plated in myeloid differentiation promoting culture and assayed for CD11b expression after 7 days.

See also Figure S3.