Table 1. Histone methyltransferases.

The histone methyltransferases for various lysine and arginine residues are indicated over the specific residues that they have been shown to methylate. Histone methyltransferases, that methylate multiple residues or methylate residues to varying degrees are written over each modification that has been reported. ‘?’ indicates results have not been independently replicated. *: PRMT-1 was shown to mono and asymmetrically dimethylate Histone H4 but the specific residue, which it methylates has not yet been identified. References for individual methyltransferases can be found in Supplementary Information.