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. Author manuscript; available in PMC: 2015 May 15.
Published in final edited form as: Immunity. 2014 May 1;40(5):681–691. doi: 10.1016/j.immuni.2014.04.006

Figure 5. Antigen Stimulation Induces Mdm2 and Termination of p53 Expression.

Figure 5

Trp53 and Mdm2 mRNA expression upon stimulation with Ag-APC + IL-2 or IL-2 alone. KLH-specific clones were stimulated as indicated. mRNA expression was measured by real-time qPCR and normalized to Gapdh mRNA expression. The graphs are mean ± SEM of three WT clones and representative of three independent experiments.