Table 2.
Functional enrichment of the complexes detected using only the unweighted PPI network
| Network | Algorithm | <E(-15) | E(-15) to E(-10) | E(-10) to E(-5) | E(-5) to 1 |
|---|---|---|---|---|---|
| Collins |
GMFTP |
33 (18.4%) |
24 (13.4%) |
60 (33.5%) |
62 (34.6%) |
| |
Linkcomm |
53 (13.0%) |
59 (14.5%) |
109 (26.8%) |
186 (45.7%) |
| |
SR-MCL |
38 (11.3%) |
36 (10.7%) |
92 (27.3%) |
171 (50.7%) |
| Gavin |
GMFTP |
29 (10.7%) |
20 (7.4%) |
54 (19.9%) |
168 (62.0%) |
| |
Linkcomm |
29 (4.8%) |
34 (5.6%) |
112 (18.5%) |
429 (71.0%) |
| |
SR-MCL |
49 (6.7%) |
29 (3.9%) |
135 (18.4%) |
522 (71.0%) |
| Krogan core |
GMFTP |
28 (10.4%) |
22 (8.1%) |
63 (23.3%) |
157 (58.1%) |
| |
Linkcomm |
24 (5.6%) |
30 (7.1%) |
114 (26.8%) |
257 (60.5%) |
| |
SR-MCL |
80 (4.4%) |
70 (3.8%) |
264 (14.4%) |
1419 (77.4%) |
| Krogan extended |
GMFTP |
29 (10.9%) |
19 (7.2%) |
57 (21.5%) |
160 (60.4%) |
| |
Linkcomm |
30 (3.0%) |
41 (4.1%) |
158 (15.8%) |
769 (77.1%) |
| |
SR-MCL |
135 (5.1%) |
86 (3.3%) |
259 (9.8%) |
2164 (81.8%) |
| DIP |
GMFTP |
36 (9.6%) |
29 (7.7%) |
68 (18.1%) |
242 (64.5%) |
| |
Linkcomm |
44 (2.4%) |
63 (3.4%) |
323 (17.7%) |
1398 (76.5%) |
| |
SR-MCL |
174 (5.4%) |
117 (3.6%) |
398 (12.3%) |
2533 (78.6%) |
| BioGRID |
GMFTP |
66 (15.2%) |
38 (8.8%) |
113 (26.0%) |
217 (50.0%) |
| |
Linkcomm |
217 (4.9%) |
254 (5.7%) |
1026 (23.1%) |
2949 (66.3%) |
| SR-MCL | 166 (15.1%) | 77 (7.0%) | 210 (19.2%) | 643 (58.7%) |