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. 2014 May 29;3(7):792–800. doi: 10.5966/sctm.2013-0216

Figure 2.

Figure 2.

Globin expression in erythroid cells derived from several hPSC clones or CB. (A): Cell sources for hiPSC generation using Sendai virus-mediated transduction. Cell sources are indicated on the left, and the derived clones are on the right. (B): mRNA expression of human ε-globin, γ-globin, and β-globin on day 18 of culture in erythroid cells derived from hESCs (KhES-3 or H1), hiPSCs (clones 1–8), and CB. (C): Time course of the changes in the indicated globins over the 18-day culture period (n = 3, symbols are means ± SD from three independent experiments). Abbreviations: CB, cord blood; HBB, β-globin; human HBE1, human ε-globin; HBG1/HBG2, human γ-globin; hESCs, human embryonic stem cells; hiPSCs, human induced pluripotent stem cells.