Table. Virulence genes associated with Corynebacterium ulcerans present in strain RAH1 isolated from patient with diphtheria-like disease, 2013, United Kingdom*.
| Gene | Strains | Strain RAH1 | Potential function |
|---|---|---|---|
| tox | 0102 | P | Diphtheria-like toxin |
| rbp | 809 | A | Shiga toxin–like ribosome binding protein |
| cpp | 809, BR-AD22, 0102 | P | Corynebacterial protease CP40, protective antigen against caseous lymphadenitis |
| pld | 809, BR-AD22, 0102 | P | Toxic phospholipase D |
| spaF | 809, BR-AD22, 0102 | P | Surface-anchored protein, pilus tip protein |
| spaE | 809, BR-AD22, 0102 | P | Surface-anchored protein, minor pilin subunit |
| spaD | 809, BR-AD22, 0102 | P | Surface-anchored protein, major pilin subunit |
| spaC | 809, BR-AD22, 0102 | P† | Surface-anchored protein, pilus tip protein |
| spaB | 809, BR-AD22, 0102 | P | Surface-anchored protein, minor pilin subunit |
| rpfI | 809, BR-AD22, 0102 | P | Resuscitation-promoting factor interacting protein |
| cwlH | 809, BR-AD22, 0102 | P | Cell wall–associated hydrolase |
| nanH | 809, BR-AD22, 0102 | P | Neuraminidase, glycosyl hydrolases |
| vsp1 | 809, BR-AD22 | P | Venom serine protease |
| vsp2 | 809 | P | Venom serine protease |
| tspA | 809, BR-AD22 | P | Trypsin-like serine protease |
*P, present; A, absent. †≈700 bp deletion.