Table 3.
Electrophysiological characteristics of STN neurons in dystonia and Parkinson's disease (PD) subtypes
Factor | Dystonia | Parkinson's Disease (Akinetic–Rigid) | P | Parkinson's Disease (Tremor Dominant) | P |
---|---|---|---|---|---|
Number of neurons | 62 | 93 | 50 | ||
Mean firing rate, Hz | 26.30 (13.6) | 35.00 (15.2) | <0.001* | 36.70 (15.1) | <0.001* |
Burst index | 7.20 (4.0) | 4.70 (2.5) | <0.001* | 4.70 (2.7) | <0.001* |
Proportion of discharges in bursts† | 0.26 (0.14) | 0.19 (0.13) | 0.001* | 0.20 (0.51) | 0.02* |
L-statistic | 7.10 (1.5) | 6.70 (1.7) | 0.05 | 6.80 (1.7) | 0.28 |
Proportion of cells with significant oscillations | |||||
0–200 Hz | 32.3% | 39.8% | 0.64 | 40.0% | 0.64 |
3–30 Hz | 6.5% | 20.4% | 0.05 | 20.0% | 0.05 |
13–30 Hz | 0.0% | 6.5% | 0.09 | 6.0% | 0.09 |
Values are means and SD (in parentheses).
Denotes statistically significant difference between dystonia and PD subtype identified in the preceding column by Wilcoxon rank-sum test or chi-squared test.
As determined using the Poisson “surprise” method.