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Significant decrease in fast-rate phasic activity in RSM in terms of rate (A and B) and amplitude (C and D), following pretreatment of the smooth muscle with different concentrations of the ROCK inhibitor Y-27632 (**P < 0.01, n = 5). Note that the PKC inhibitor calphostin C has no effect on rate or amplitude (P > 0.05, n = 5), while Gö-6850 also has no significant effect on rate (P > 0.05, n = 5) but causes a small, but significant, decrease in amplitude (*P < 0.05).
