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. 2013 Feb 14;304(8):G723–G731. doi: 10.1152/ajpgi.00473.2012

Fig. 6.

Fig. 6.

Effects of calphostin C, Gö-6850, Y-27632, and Gö-6850 + Y-27632 in maximally effective concentrations (10−5 M) on fast-rate phasic activity in RSM. Although the ROCK inhibitor Y-27632 causes a significant decrease in rate (A and B) and amplitude (C and D; *P < 0.05, n = 5), PKC inhibitors have no significant effect on fast-rate phasic activity in RSM (A–D). Gö-6850 + Y-27632 does not produce a further significant decrease in RSM activity compared with Y-27632 alone (P > 0.05). Note that 0 Ca2+ nearly abolishes fast-rate phasic activity in RSM (*P < 0.05, n = 5).