Table 2.
Demographic and clinical characteristics of the Chicago samples
| Sepsis-Associated ARDS |
Controls |
|||
|---|---|---|---|---|
| AD | ED | AD | ED | |
| Number | 34 | 71 | 185 | 186 |
| Sex, male/female | 15/19 | 40/31 | 51/134 | 83/103 |
| Age | 44.6 ± 15.4 | 58.6 ± 16.9 | 54.8 ± 17.4 | 55.6 ± 12.4 |
| APACHE II | 28.0 ± 7.7 | 29.7 ± 7.4 | NA | NA |
| PaO2/FiO2, mmHg | 121 ± 51.9 | 128 ± 62.4 | NA | NA |
| Survival, % | 52.4 | 62.0 | NA | NA |
| Smoking history, % | 34.2 | 40.3 | Unavailable | Unavailable |
| Comorbidity | ||||
| Cancer, % | 11.9 | 21.8 | 0.0 | 0.0 |
| CLD, % | 4.9 | 13.9 | 0.0 | 0.0 |
| Diabetes, % | 16.7 | 19.0 | 0.0 | 0.0 |
| COPD, % | 2.4 | 14.3 | 0.0 | 0.0 |
| AIDS, % | 19.0 | 2.5 | Unavailable | Unavailable |
| Organ failure | ||||
| Renal failure, % | 21.4 | 19.0 | 0.0 | 0.0 |
| Anemia, % | 9.5 | 7.7 | 0.0 | 0.0 |
| Site of infection* | ||||
| Lung, % | 71.4 | 73.4 | NA | NA |
| Abdomen/GI, % | 11.9 | 19.0 | NA | NA |
| UTI, % | 9.5 | 10.1 | NA | NA |
| Other, % | 21.4 | 21.5 | NA | NA |
AD, African descent; ED, European descent; ARDS, acute respiratory distress syndrome; APACHE II, Acute Physiology and Chronic Health Evaluation; PaO2/FiO2, ratio of partial pressure of arterial O2 to the fraction of inspired O2; CLD, chronic liver disease; COPD, chronic obstructive pulmonary disease; AIDS, acquired immunodeficiency syndrome; NA, not applicable; GI, gastrointestinal; UTI, urinary tract infection.
*
More than 1 site of infection is listed for some patients; sum of percentages exceeds 100%.