Table 1. Summary of EDL muscle electrophysiological properties in wild-type (WT) and Sod1 −/− mice.
WT | Sod1 −/− | |
Number of mice (total number of NMJ) | N = 4 (20) | N = 5 (24) |
Resting membrane potential (mV) | −73.32±0.53 | −71.73±1.43 |
Input resistance (MOhm) | 2.71±0.04 | 2.04±0.31 |
mEPP amplitude (mV) | 0.46±0.03 | 0.44±0.02 |
mEPP frequency (Hz) | 3.74±0.59 | 0.78±0.12** |
t(1/2) of mEPP, (ms) | 2.07±0.06 | 2.10±0.04 |
EPP amplitude (mV) | 27.70±1.61 | 19.70±1.71* |
Quantal content | 93±8 | 63±8* |
Values are mean ± standard errors. N depicts the number of animals used, and n depicts the total number of NMJs sampled. Statistics: t-test, *p<0.05 and **p<0.01.