Table 1. Comparison of demographic data and YAP expression between type 1 and type 2 EMCA.
Type1 cancer (n = 120) | Type2 cancer (n = 30) | P-value | ||
Age (year) | mean (range) | 63.6 (40–89) | 67.4 (47–85) | N.S.(a) |
BMI | mean (range) | 36.8 (19.1–70.4) | 35 (18.4–85.4) | N.S.(a) |
Ethnic group | White | 119 | 29 | |
Other races | 1 | 1 | N.S.(b) | |
Grade | 1 | 103 | 0 | |
2/3 | 17 | 30 | p<0.0001(b) | |
Stage | I/II | 53 | 56 | |
III/IV | 1 | 10 | p = 0.028(b) | |
LVSI | Absent | 99 | 13 | |
Present | 21 | 17 | p<0.0001(b) | |
Recurrence/Metastasis | Absent | 110 | 17 | |
Present | 10 | 13 | p<0.0001(b) | |
Nuclear YAP score | 0 | 23 | 1 | |
1 | 31 | 2 | ||
2 | 20 | 8 | ||
3 | 16 | 7 | ||
4 | 30 | 12 | ||
Low (score: 0/1) | 54 | 3 | ||
High (score: 2/3/4) | 66 | 27 | p = 0.0009(b) | |
Cytoplasmic YAP score | 0 | 3 | 0 | |
1 | 14 | 0 | ||
2 | 21 | 11 | ||
3 | 40 | 9 | ||
4 | 42 | 10 | ||
Low (score: 0/1/2) | 38 | 11 | ||
High (score: 3/4) | 82 | 19 | N.S.(b) |
BMI; Body mass index, LVSI; Lymphovascular space involvement, N.S.; not significant.
(a): Student's t-test, (b): Chi square test (there is no <10 number in data)/Fisher's exact test (there is <10 number in data).