Table 2.

Change in level of functioning per QLS total and QLS subscale scores from baseline to last observation, by treatment group

QLS score/visit	Olanzapine-LAIa	Pb	Oral olanzapine	Pb
QLS total score, mean (SD)
Baseline	64.0 (21.2)	<0.001	62.1 (18.8)	<0.001
Last observation years	70.8 (22.9)		70.1 (22.4)
QLS common objects and activities, mean (SD)
Baseline	6.6 (2.6)	<0.001	6.5 (2.5)	<0.001
Last observation	7.3 (2.6)		7.1 (2.6)
QLS intrapsychic foundation, mean (SD)
Baseline	21.9 (7.9)	<0.001	21.6 (6.9)	<0.001
Last observation	24.1 (8.7)		23.9 (8.4)
QLS intrapersonal relation, mean (SD)
Baseline	21.0 (10.0)	<0.001	20.0 (9.3)	<0.001
Last observation	24.2 (10.2)		23.9 (10.0)
QLS instrumental role, mean (SD)
Baseline	14.1 (3.6)	<0.001	13.9 (3.2)	<0.001
2 years	14.8 (3.9)		14.8 (3.8)

Note:

^aThere were no statistical differences between olanzapine-LAI and oral olanzapine in any of the ratings.

^bP value; change from baseline to endpoint.

Abbreviations: LAI, long-acting injection; SD, standard deviation; QLS, Quality of Life Scale.