Table 1.
The clinicopathological features of patients at PUMCH
| Case | Age (years) | Primary site | Presenting symptom | Preoperative diagnosis | Metastasis | Chemotherapy | Surgery | Histology | Death | Outcome | OS (months) |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 28 | Testis | Testis enlargement | No | Lung, brain | FAEV × 3 | Orchiectomy | CC + IMT | Yes | Progress | >6 |
| 2 | 17 | Testis | Mass on testis | No | No | EMA/CO × 8; EMA/EP × 2 | Orchiectomy | CC + MT | No | Complete remission | 138 |
| 3 | 42 | Testis | Mass on testis | No | Lung | EMA/CO × 4; EMA/EP × 7 | Orchiectomy, Metastatic tumor resection | CC + embryonal carcinoma | No | Complete remission | 54 |
| 4 | 35 | Testis | Mass on testis | No | No | No | Orchiectomy | CC + MT | No | Complete remission | 53 |
| 5 | 33 | Mediastinum | Hemoptysis | No | Lung | PVB/PEB × 5; EMA/CO × 5: EMA/EP × 5; IEP × 6; MEP × 3; other × 3 | Lung lesion resection, mediastinal biopsy | CC | No | Complete remission | 115 |
| 6 | 24 | Mediastinum | Coughing, hemoptysis, mediastinal mass | Yes | No | EMA/CO × 3; PEB × 3 | Mediastinal tumor partial resection | CC | Yes | Progress | 9 |
| 7 | 31 | Mediastinum | Dysphagia | No | Lung | EMA/CO × 6; EP × 1; PVE × 3 | Mediastinal tumor resection | CC + IMT | Yes | Progress | 9 |
| 8 | 16 | Pineal body | Intracranial hypertension symptoms | No | Lung | EMA/CO × 2; FAEV × 5 | Emergency craniotomy, total resection of tumor | CC | Yes | Progress | 7 |
| 9 | 6 | Pineal body | Peripheral precocious puberty | Yes | No | IFO + DDP + VP16 × 3 | Craniotomy, total resection of tumor | CC | No | Complete remission | 13 |
| 10 | 45 | Lung | Fainting | No | Brain | EMA/CO × 9 | Left occipital craniotomy, lung biopsy | CC | Yes | Relapse | 10 |
| 11 | 49 | Retroperitoneal | Retroperitoneal mass | No | Lung, bone | VAC × 3; PVB × 3; EMA/CO × 5 FAEV × 4; MTX × 4 | Total resection of tumor, Metastatic tumor resection | CC + IMT | Yes | Relapse | 54 |
| 12 | 52 days | Jejunum | Hematochezia | No | Lung | EMA × 1; MTX × 3 | Partial jejunum resection | CC | No | Complete remission | 60 |
| 13 | 55 | Stomach | Stomach discomfort | Yes | Liver, retroperitoneal | EMA/CO × 4; FAEV × 1 | Subtotal gastrectomy | CC | Yes | Progress | 6 |
Abbreviations: CC, choriocarcinoma; EMA/CO, actinomycin D, etoposide, methotrexate, cyclophosphamide, vincristine; EMA/EP, actinomycin D, etoposide, methotrexate, cisplatin (DDP); FAEV, 5-fluorouracil, actinomycin D, etoposide; IEP, carboplatin, etoposide, ifosfamide (IFO); IMT, immature teratoma; MEP, cisplatin, mitomycin, etoposide; MT, mature teratoma; PUMCH, Peking Union Medical College Hospital; PVB/PEB, cisplatin, vincristine, bleomycin/vincristine; VAC, vincristine, actinomycin D, cyclophosphamide; OS, overall survival; PVE, vindesine, cisplatin, etoposide; VP16, etoposide; MTX, methotrexate.