Fig. 4.

Cells subsequently delaminate from the neural ectoderm in both mouse and chicken embryos. A second population of cells delaminates from the neural ectoderm. To the left are schematics of the embryos shown in the images, with the plane of section illustrated. Parts a-d show an overview, whereas e-h show a higher magnification of the neural fold. (A) Eight-somite mouse embryo. Sox9 is expressed in the dorsal neural ectoderm that is expressing Sox1; delaminated cells are indicated (white dotted line). (B) Seven-somite chicken embryo. N-cadherin is more strongly expressed in the neural ectoderm, whereas E-cadherin expression in the neural ectoderm is reduced. Snail2 is expressed in the N-cadherin-positive neural epithelia (white dotted line) and in migrating cells juxtaposed between the neural and non-neural ectoderm. Scale bars: 20 μm.