Table 4.
Genes that show testosterone-driven changes in both CpG methylation and gene expression
| Gene | Log 2 fold change | Expression difference p value | Δ Me at PN60 |
|---|---|---|---|
| Ppp2r5c |
1.07 |
9.66E − 05 |
0.10 |
| Nrxn1 |
0.95 |
3.63E − 04 |
0.10 |
| Lpin1 |
0.71 |
8.18E − 05 |
0.10 |
| Egln1 |
0.53 |
2.41E − 04 |
0.13 |
| Bin1 |
0.47 |
2.08E − 04 |
0.11 |
| Inpp5a |
0.42 |
3.80E − 04 |
−0.13 |
| Fhl1 |
0.40 |
4.11E − 05 |
0.15 |
| Mras |
−0.42 |
3.09E − 04 |
0.13 |
| E130203B14Rik |
−0.61 |
2.75E − 04 |
0.12 |
| Wfdc1 | −0.66 | 1.26E − 04 | 0.10 |
Genes that show testosterone-driven changes in both CpG methylation and gene expression in the PN60 XX vs. XX + T comparison in the striatum. Negative values in the second column indicate lower expression in XX + T relative to XX. In the fourth column, negative values indicate lower methylation in XX + T relative to XX.