Table 3.
Statistical indices of clinical decision support system diagnostic performance
| |
Migraine |
TTH |
CH |
MOH |
NDPH |
||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| MO | MA | CM | PM | iETTH | fETTH | CTTH | PTTH | ||||
| Sensitivity (%) |
99.38 |
100 |
95.24 |
62.71 |
92.31 |
98.02 |
90 |
60.87 |
90 |
100 |
100 |
| (95% CI) |
96.55- 99.89 |
|
77.33-99.15 |
49.95-73.92 |
66.69- 98.63 |
93.07-99.46 |
69.9-97.21 |
46.46-73.61 |
74.38-96.54 |
||
| Specificity (%) |
97.91 |
100 |
99.62 |
98.76 |
99.81 |
99.55 |
99.43 |
97.99 |
99.61 |
100 |
100 |
| (95% CI) |
95.93- 98.94 |
|
98.61-99.89 |
97.32-99.43 |
98.94-99.97 |
98.37- 99.88 |
98.33-99.8 |
96.34-98.9 |
98.59-99.89 |
||
| Coincidence (%) |
98.34 |
100 |
99.45 |
94.84 |
99.63 |
99.26 |
99.08 |
94.84 |
99.08 |
100 |
100 |
| (95% CI) |
96.88-99.13 |
|
98.39- 99.81 |
92.65-96.41 |
98.67-99.9 |
98.12-99.71 |
97.86-99.61 |
92.65-96.41 |
97.86-99.61 |
||
| False negative rate |
0.01 |
0 |
0.05 |
0.37 |
0.08 |
0.02 |
0.10 |
0.39 |
0.10 |
0 |
0 |
| False positive rate |
0.02 |
0 |
0.01 |
0.02 |
0.01 |
0.01 |
0.01 |
0.02 |
0.01 |
0 |
0 |
| Youden index |
0.97 |
1 |
0.94 |
0.61 |
0.92 |
0.98 |
0.89 |
0.59 |
0.90 |
1 |
1 |
| PPV (%) |
95.21 |
100 |
90.91 |
86.05 |
92.31 |
98.02 |
85.71 |
73.68 |
93.1 |
100 |
100 |
| (95% CI) |
90.83-97.55 |
|
72.18-97.47 |
72.74- 93.44 |
66.69-98.63 |
93.07-99.46 |
65.36-95.02 |
57.99-85.03 |
78.04-98.09 |
|
|
| NPV (%) |
99.73 |
100 |
99.81 |
95.6 |
99.81 |
99.55 |
99.62 |
96.44 |
99.42 |
100 |
100 |
| (95% CI) |
98.51-99.95 |
|
98.92- 99.97 |
93.43-97.08 |
98.94-99.97 |
98.37-99.88 |
98.61-99.89 |
94.44-97.73 |
98.3-99.8 |
||
| κ |
0.9606 |
1 |
0.9274 |
0.6978 |
0.9212 |
0.9757 |
0.8733 |
0.639 |
0.910 |
1 | 1 |
| (95% CI) | 0.8766-1.045 | 0.8433- 1.011 | 0.615 - 0.7807 | 0.8371 - 1.005 | 0.8916 - 1.06 | 0.789-0.957 | 0.555-0.723 | 0.826-0.995 | |||
MO: migraine without aura; MA: Migraine with aura; CM: chronic migraine; PM: probable migraine; TTH: tension-type headache; iETTH: infrequent episodic tension-type headache; fETTH: Frequent episodic tension-type headache; CTTH: chronic tension-type headache; PTTH: probable tension-type headache; CH: cluster headache; MOH: medication overuse headache; CI: confidence interval; PPV: positive predictive value; NPV: negative predictive value; κ: Cohen’s kappa.