Table 3.
Comparison of morphological and metabolic indices on FDG PET between HPV positive OPCC patients based on smoking history (median and range)
| smokers | Non-smokers | ||
|---|---|---|---|
| Primary | |||
| SUVmax | 9.7 (2.9 – 19.9) | 10.7 (3.6 – 21.6) | p=0.6 |
| SUVmean | 4.9 (1.9 – 10.0) | 5.5 (2.0 – 10.5) | p = 0.6 |
| SUVpeak | 9.1 (4.2 – 16.9) | 9.2 (3.9 – 18.1) | p = 0.9 |
| MTVedge (cm3) | 7.5 (1.0 – 63.5) | 9.7 (0.5 – 164.5) | p = 0.3 |
| TLGedge (cm3) | 34.5 (2.7 – 635.9) |
55.3 (1.3 – 413.5) | p = 0.4 |
| MTVthreshold (cm3) | 3.3 (0.4 – 34.7) | 4.9 (0.4 – 33.0) | p = 0.6 |
| TLGthreshold (cm3) | 24.1 (1.4 – 452.0) |
34.6 (1.1 – 215.2) | p = 0.5 |
| PERCIST long (cm) | 2.5 (1.3 – 5.5) | 2.8 (1.0 – 7.4) | P = 0.5 |
| HI | 1.8 (1.4 – 2.4) | 1.9 (1.3 – 3.2) | p = 0.4 |
| MI | 2.9 (0.7 – 11.9) | 3.2 (0.5 – 22.3) | p = 0.3 |
| Nodal | |||
| Highest SUVmax | 8.2 (3.5 – 22.9) | 7.4 (3.2 – 16.9) | p = 0.4 |
| Highest SUVpeak | 7.0 (3.3 – 17.5) | 6.2 (2.8 – 30.4) | p = 0.9 |
| highest MTVedge (cm3) | 13.6 (0.6 – 118.2) |
7.2 (1.5 – 148.1) | p = 0.1 |
| Highest RECISTlong (cm) | 3.1 (1.4 – 7.8) | 2.6 (1.4 – 7.8) | p =0.07 |
| Highest TLGedge | 46.9 (1.4 – 339.0) |
28.3 (3.5 – 807.1) | p = 0.06 |
| Sum TLGedge | 50.2 (1.4 – 437.1) |
43.2 (3.5 – 807.1) | p = 0.3 |
| Sum MTVthreshold | 5.0 (0.9 – 68.2) | 5.2 (0.7 – 48.4) | p = 0.7 |
| Sum TLGthreshold | 26.5 (3.5 – 223.2) |
24.6 (1.7 – 412.3) | p = 0.3 |
| HI | 2.0 (1.4 – 2.9) | 1.9 (1.6 – 3.0) | p = 0.3 |
| MI | 3.9 (0.4 – 15.2) | 2.9 (1.0 – 18.9) | p = 0.1 |
MTV: metabolic tumor volume, TLG: total lesion glycolysis, HI: heterogeneity index, MI: metabolic index