Table.
Demographic and clinical characteristics of study subjects
| Initial empirical antibiotic therapy, n = infants (% of total study infants) | ||||
|---|---|---|---|---|
| Variable, description | 0 Days n = 13 (17.6) | 1-4 Days, n = 48 (64.8) | 5-7 Days n = 13 (17.6) | P value* |
| Infant baseline characteristics | ||||
| Birth weight, median (range) (g) | 1305 (890-1500) | 1065 (520-1480) | 750 (510-1440) | 0.001 |
| Gestational age, median (range) (wk) | 31 (24-32) | 28 (24-32) | 25 (23-31) | < 0.001 |
| Non-Hispanic black, no. (%) | 3 (23.1) | 10 (20.8) | 7 (53.8) | 0.071 |
| Male, no. (%) | 2 (15.4) | 26 (54.2) | 6 (46.2) | 0.046 |
| Cases, no. (%) | 0 (0) | 9 (18.8) | 5 (38.5) | 0.044 |
| Maternal and prenatal information | ||||
| Prenatal steroids given (any), no. (%) | 13 (100) | 42 (87.5) | 11 (84.6) | 0.553 |
| Hypertension / Pre-eclampsia, no. (%) | 12 (92.3) | 6 (12.5) | 4 (30.8) | < 0.001 |
| Prenatal care (≥ 1 prenatal visit), no. (%) | 13 (100) | 47 (97.9) | 13 (100) | 1 |
| Antepartum hemorrhage, no. (%) | 0 (0) | 12 (25) | 1 (7.7) | 0.069 |
| Multiple birth, no. (%) | 5 (38.5) | 17 (35.4) | 2 (15.4) | 0.417 |
| Antepartum antibiotic therapy, no. (%) | 4 (30.8) | 25 (52.1) | 8 (61.5) | 0.311 |
| Labor and delivery information | ||||
| Cesarean delivery, no. (%) | 12 (92.3) | 31 (64.6) | 8 (61.5) | 0.151 |
| Chorioamnionitis, no. (%) | 0 (0) | 5 (10.4) | 2 (15.4) | 0.443 |
| Delivery room resuscitation, no. (%) | 8 (61.5) | 29 (60.4) | 12 (92.3) | 0.100 |
| Rupture of membranes > 18 hrs, no. (%) | 0 (0) | 9 (18.8) | 7 (53.8) | 0.003 |
*
P-values calculated by Fisher exact test for categorical values (%) and ANOVA for continuous variables (birth weight, gestational age)