TABLE 6.
Adjusted Difference in mortality and complications of prematurity for infants between 500 and 1500 g birth weight delivering at a high-level NICU compared with other delivery hospitals, Pennsylvania, California, and Missouri 1995–2005
| Outcome | Statistic | Pennsylvania | California | Missouri |
|---|---|---|---|---|
| Mortality measures | ||||
| All hospital death | RD per 100 deliveriesa | −5.7 (−11.0 to −0.4)b | −5.3 (−8.5 to −2.0)b | −0.4 (−10.7 to 9.8) |
| RRc | 0.68 (0.44–0.96)b | 0.77 (0.66–0.91)b | 0.98 (0.60–1.76) | |
| Neonatal death | RD per 100 deliveries | −5.9 (−11.0 to −0.8)b | −2.6 (−5.6 to 0.4) | 0.5 (−9.2 to 10.1) |
| RR | 0.63 (0.40–0.94)b | 0.85 (0.71–1.04) | 1.03 (0.61–2.06) | |
| Preventable fetal death | RD per 100 deliveries | 0.2 (−1.7 to 2.1) | −2.7 (−4.4 to −0.9)b | −0.9 (−5.7 to 3.9) |
| RR | 1.13 (0.27–5.40) | 0.56 (0.38–0.78)b | 0.75 (0–8.0) | |
| Complication measures | ||||
| BPD | RD per 100 deliveries | 4.0 (−2.6 to 10.5) | 3.5 (0.2–6.8) | −21.9 (−32.9 to −10.9)b |
| RR | 1.22 (0.88–1.70) | 1.33 (1.03–1.81) | 0.29 (0.12–0.52)b | |
| NEC | RD per 100 deliveries | 3.9 (0.1–7.6)b | 0.7 (−1.4 to 2.7) | −2.1 (−8.0 to 3.8) |
| RR | —d | 1.12 (0.79–1.67) | 0.78 (0.32–1.67) | |
| Fungal sepsis | RD per 100 deliveries | 0.7 (−2.1 to 3.5) | −2.1 (−4.1 to 0)b | −4.1 (−11.3 to 3.0) |
| RR | 1.47 (0–27.1) | 0.52 (0.22–0.96)b | 0.51 (0.07–2.06) | |
| Bacterial sepsis | RD per 100 deliveries | 13.6 (7.1–20.9)b | −1.7 (−5.5 to 2.1) | −8.1 (−20.1 to 3.8) |
| RR | 2.64 (1.65–6.03)b | 0.93 (0.79–1.11) | 0.79 (0.56–1.13) | |
| ROP | RD per 100 deliveries | −1.4 (−5.9 to 3.1) | 12.0 (8.4–15.5)b | −6.2 (−17.8 to 5.4) |
| RR | 0.68 (0–3.67) | 2.46 (1.82–3.67)b | 0.84 (0.60–1.19) | |
| Surgery for ROP | RD per 100 deliveries | 1.1 (−1.1 to 3.3) | 3.5 (1.8–5.1)b | −3.9 (−9.4 to 1.7) |
| RR | —d | —d | 0.50 (0.08–1.47) | |
| Laparotomy | RD per 100 deliveries | 0 (−2.2 to 2.2) | −1.5 (−3 to 0) | −1.6 (−6. to 2.7) |
| RR | 1 (0–8.0) | 0.65 (0.39–1.06) | 0.63 (0–2.75) | |
| Any IVH | RD per 100 deliveries | 12.5 (6.5–18.5) | 3.0 (0–6.1) | −7.8 (−18.3 to 2.5) |
| RR | —d | —d | —d |
All values in parentheses indicate 95% confidence intervals for a given statistic.
A positive RD indicates a higher rate at high-level NICUs compared with other delivery hospitals. A negative RD indicates a lower rate at high-level NICUs compared with other delivery hospitals.
All results statistically significant at a P < .05 level.
A RR >1 indicates a higher rate at high-level NICUs compared with other delivery hospitals. A RR <1 indicates a lower rate at high-level NICUs compared with other delivery hospitals.
RR calculations were unstable because of the limited number of events occurring at other delivery hospitals or at high-level NICUs.