TABLE 2.
Comparison of CVA6-Positive Cases to Cases Without CVA6 Confirmation, No. Positive / Total No. Reported (%)a
| All Cases | CVA6+ Cases | Cases Without CVA6 Confirmation | P | |
|---|---|---|---|---|
| (n = 80) | (n = 17) | (n = 63) | ||
| Age, y, median (range) | 1.5 (0.33–16) | 1.25 (0.33–16) | 1.58 (0.33–16) | .59 |
| Sex | ||||
| Female | 42/80 (53%) | 12/17 (71%) | 30/63 (48%) | .11 |
| Male | 38/80 (48%) | 5/17 (30%) | 33/63 (52%) | |
| Body surface area | ||||
| <10% | 27/69 (39%) | 6/12 (50%) | 21/57 (37%) | .34 |
| 11%–25% | 18/69 (26%) | 4/12 (33%) | 14/57 (25%) | |
| >26% | 25/69 (35%) | 2/12 (17%) | 23/57 (39%) | |
| Distribution | ||||
| Palm/soles | 67/80 (84%) | 15/17 (88%) | 52/63 (83%) | .72 |
| Extremities | 79/79 (100%) | 17/17 (100%) | 62/62 (100%) | — |
| Face | 62/79 (79%) | 12/17 (71%) | 50/62 (81%) | .51 |
| Torso | 45/80 (56%) | 12/17 (70%) | 33/63 (52%) | .27 |
| Buttocks, groin, perineum | 55/72 (76%) | 12/17 (71%) | 43/55 (78%) | .53 |
| Morphology | ||||
| Vesicle, bullae, or erosions | 79/80 (99%) | 17/17 (100%) | 62/63 (98%) | 1.00 |
| Eczema herpeticum-like | 44/80 (55%) | 6/17 (35%) | 38/63 (60%) | .10 |
| Gianotti-Crosti-like | 28/76 (37%) | 8/16 (50%) | 20/60 (33%) | .25 |
| Purpuric/petechial | 13/78 (17%) | 3/17(18%) | 10/61 (16%) | 1.00 |
| Accentuation in areas of skin injury | 14/76 (18%) | 4/17 (24%) | 10/59 (17%) | .50 |
| Oral erosions/ulcerations | 39/77 (51%) | 9/17 (53%) | 30/60 (50%) | 1.00 |
| Nail changes | 9/38 (24%) | 2/8 (25.0%) | 7/30 (23%) | 1.00 |
| Hospitalized | 10/80 (13%) | 2/17 (12%) | 8/63 (13%) | 1.00 |
| Fever | 56/75 (75.0%) | 11/14 (79%) | 45/61 (74%) | 1.00 |
| Illness duration, d; (mean ± SD) | 12.2 ± 7.0 (n = 39) | 8.8 ± 3.6 (n = 12) | 13.7 ± 7.7 (n = 27) | .07 |
a
Not all features were known for each patient. Patients could be reported as having multiple morphologies and distributions. Percentages were rounded and do not add up to 100%. —, indicates P value can not be calculated when the condition is present in 100% of patients.