TABLE 3.

Rates and Numbers of Errors by Medication and Errors in Chemotherapy, Supportive Medications for Safe Administration of Chemotherapy, and Other Medications

Medication	Site A	Site B	Site C
Total medications reviewed	335	510	118
Median medications per child (range)	10 (3–26)	12 (5–23)	7 (3–13)
Administrations observed	96	105	41
Crude error rate per 100 medications	12	3	13
Adjusted error rate per 100 medicationsa	9.6 (7.5–11.7)	3.0 (0.9–4.1)	15.0 (11.4–18.6)
Chemotherapy medications	72	74	43
Chemotherapy errors	8	2	4
Supportive medications	32	45	13
Supportive medication errorsb	2	0	1
Antibiotics, antiviral agents, antifungal	56	70	19
Antibiotics, antiviral agents, antifungal errors	11	4	4
Gastrointestinal medications	62	119	3
Gastrointestinal medication errors	1	4	1
NSAIDS and local anesthetics	22	45	3
NSAIDs and local anesthetic errors	3	0	1
Narcotics	19	51	8
Narcotic errors	2	2	1
Respiratory medications	8	5	1
Respiratory medication errors	3	0	0
Antiepileptic/neurologic medications	9	36	7
Antiepileptic/neurologic medications errors	0	0	0
Allergy medication	16	11	8
Allergy medication errors	3	1	2
Vitamins	13	14	0
Vitamin errors	1	0	0
Topical agent	7	8	1
Topical agent errors	1	0	0
Behavior/mental health medications	8	9	8
Behavior/mental health medication errors	4	2	1
Other medications	11	23	1
Other medication errors	1	1	0

Supportive medications included antiemetic agents and other medications included methylphenidate for attention-deficit disorder or medications for Pneumocystis prophylaxis. NSAIDs, nonsteroidal antiinflammatory drugs.

^aThe adjusted rate per medication was weighted to account for clustering by individual patient.

^bSupportive medications were those required to support safe chemotherapy use.