TABLE 1.
Category | Criteria |
---|---|
Study population | Prepubescent males presenting with cryptorchidism or suspected cryptorchidism |
Interventions | Hormones, including hCG or gonadotropin-releasing hormone, surgical therapy, and specific surgical techniques (ie, 1-stage versus 2-stage orchiopexy, laparoscopic versus open approach) |
Comparators | Nontreatment, later treatment, hormones, and different surgical techniques |
Outcomes | • Immediate (within 6 wk of therapy) and short-term (6 wk to 2 y of therapy) outcomes: |
o Testicular size and appearance | |
o Testicular position | |
o Pain | |
o Parent/patient satisfaction | |
o Need for further surgical intervention | |
o Emotional/psychosocial response | |
o Adverse effects, including but not limited to pain, infection, hematoma, and edema | |
• Long-term (>2 y after therapy) outcomes: | |
o Testicular size and appearance | |
o Testicular position | |
o Endocrine function | |
o Body image | |
o Parent/patient satisfaction | |
o Infertility/subfertility | |
o Torsion | |
o Testicular malignancy and cancer | |
o Hernia | |
o Emotional/psychosocial response | |
Timing | Time frame for reporting of outcomes was not restricted. |
Setting | All settings were considered, including hospitals and university or academic medical centers. |
hCG, human chorionic gonadotropin.