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. 2013 Jun;131(6):e1897–e1907. doi: 10.1542/peds.2013-0072

TABLE 1.

Study Inclusion Criteria: Population, Intervention, Comparator, Outcomes, Timing, Setting

Category Criteria
Study population Prepubescent males presenting with cryptorchidism or suspected cryptorchidism
Interventions Hormones, including hCG or gonadotropin-releasing hormone, surgical therapy, and specific surgical techniques (ie, 1-stage versus 2-stage orchiopexy, laparoscopic versus open approach)
Comparators Nontreatment, later treatment, hormones, and different surgical techniques
Outcomes  • Immediate (within 6 wk of therapy) and short-term (6 wk to 2 y of therapy) outcomes:
  o Testicular size and appearance
  o Testicular position
  o Pain
  o Parent/patient satisfaction
  o Need for further surgical intervention
  o Emotional/psychosocial response
  o Adverse effects, including but not limited to pain, infection, hematoma, and edema
 • Long-term (>2 y after therapy) outcomes:
  o Testicular size and appearance
  o Testicular position
  o Endocrine function
  o Body image
  o Parent/patient satisfaction
  o Infertility/subfertility
  o Torsion
  o Testicular malignancy and cancer
  o Hernia
  o Emotional/psychosocial response
Timing Time frame for reporting of outcomes was not restricted.
Setting All settings were considered, including hospitals and university or academic medical centers.

hCG, human chorionic gonadotropin.