TABLE 2.

Humoral Immunity (CdLS Patients With Antibody Deficiency)

	Age, ya	IgG (mg/dL)	IgM (mg/dL)	IgA (mg/dL)	Tetanus Ab (IU/mL)	Diptheria Ab (IU/mL)	Pneumococcal Ab	CdLS Mutation
Reference		—b	—b	—b	>0.60 IU/mL	>0.10 IU/mL	(>1.3 ug/mL)
Patient 1c	3	365 (L)	20 (L)	44	0.3.36	1.49	1/14 (L)	NIPBL 6402–6405del4 exon 37
Patient 6c	14	363 (L)	40 (L)	66	>3.0	>0.1	1/4 (L)	n/a
Patient 8c	0	30 (L)	6	45	<0.1 (L)	0.01 (L)	0/12 (L)	n/a
Patient 12c	6	319 (L)	47.6	55.5	0.15 (L)	0.07 (L)	6/14 (L)	n/a
Patient 18d	9	554 (L)	47	132	n/a	n/a	n/a	NIPBL frameshift 6407_6408insA
Patient 9d	2	464	42 (L)	100	n/a	n/a	6/14 (L)	NIPBL 1753delA frameshift
Patient 10d	16	142	92	313	n/a	n/a	5/14 (L)	n/a
Patient 14d	20	1090	116	486	0.51	0.179	5/14 (L)	n/a
Patient 23d	42	1144	140	248	6.3	n/a	5/14 (L)	n/a

Ab, antibody; n/a, not applicable.

^aAge at the time of testing.

^bReference ranges vary with age.

^cPatient diagnosed with CVID.

^dPatient diagnosed with SAD.