Average temperature of the radial side of the right forearm (Tforearm) during the control (AIR) and the normobaric hypoxic (HYPO) cold-water hand immersion test. Values are mean±SD. ‡Significant difference from B and WWI (p≤0.05); †Significant difference from B, WWI and CWI (p≤0.001). B, a 5-min baseline phase, a 5-min warm-water hand immersion phase, a 30-min cold-water hand immersion phase; RW, a 15-min rewarming phase; WWI, a 5-min warm-water hand immersion phase.