Table 3.
Embryos kinetics during development to day 5
| Blasts transferred (BL-T) Mean ± SD | 95% CI | Blasts frozen (BL-F) Mean ± SD | 95% CI | PQ BL/Non blasts (PQ-D) Mean ± SD | 95% CI | p | |
|---|---|---|---|---|---|---|---|
|
tPNf |
24.8 ± 2.6 |
24.3- 25.3 |
25.2 ± 3.0 |
24.9 - 25.6 |
26.8 ± 8.3 |
26.6 - 28.0 |
0.001 |
|
t2 |
27.2 ± 3.6 |
26.5 - 27.8 |
27.7 ± 4.0 |
27.1-28.2 |
30.0 ± 8.8 |
28.8- 31.2 |
<0.0001 |
|
t3 |
37.6 ± 5.5 |
36.5-38.7 |
38.0 ± 5.8 |
37.4 - 38.6 |
38 ± 11.8 |
36.4- 39.6 |
ns |
|
t4 |
40.0 ± 5.4 |
39.0 - 41.1 |
40.9 ± 6.1 |
40.3- 41.6 |
43.4 ± 1 4.3 |
41.4 - 45.4 |
0.003 |
|
t5 |
52.0 ± 6.3 |
50.8 - 53.2 |
52.4 ± 9.0 |
51.5 - 53.4 |
50.2 ± 15.3 |
48.0 - 52.4 |
ns |
|
t8 |
62.1 ± 9.8 |
60.2- 64.0 |
63.8 ± 11.7 |
62.6- 65.1 |
71.1 ± 21.2 |
67.8 - 74.3 |
<0.0001 |
|
t9+ |
73.5 ± 10.3 |
71.4-75.6 |
74.7 ± 13.3 |
73.2-76.3 |
83.7 ± 24.5 |
79.7-87.8 |
<0.0001 |
|
tMor |
93.9 ± 9.8 |
91.9 - 95.9 |
98.2 ± 12.8 |
96.8 - 99.7 |
110.7 ± 15.3 |
106.7 - 114.7 |
<0.0001 |
|
tSB |
100.2 ± 7.4 |
99.0– 101.5 |
105.5 ± 10.3 |
104.5 – 106.5 |
113.1 ± 13.1 |
110.2 – 116.1 |
<0.001 |
|
tBL |
105.2 ± 6.3 |
103.8 - 106.6 |
111.1 ± 10.5 |
109.9 - 112.3 |
121.4 ± 9.1 |
116-126.0 |
<0.0001 |
|
tEBL |
110.0 ± 5.6 |
108.6 - 111.4 |
118.9 ± 12.1 |
117.3 - 120.4 |
133.1 ± 9.0 |
127.1-139.2 |
<0.0001 |
|
cc2 (t3-t2) |
10.4 ± 4.5 |
9.6- 11.3 |
10.2 ± 4.7 |
9.7- 10.8 |
8.6 ± 10.7 |
7.1 - 10.1 |
0.02 |
|
cc3 (t5-t3) |
14.4 ± 5.4 |
13.4-15.4 |
14.4 ± 7.3 |
13.6-15.1 |
14.0 ± 13.1 |
12.1-15.8 |
ns |
|
S1 (t2-tPNf) |
2.4 ± 1.7 |
2.0 – 2.7 |
2.6 ± 1.9 |
2.4 -2.8 |
3.2 ± 3.9 |
2.6 – 3.7 |
0.03 |
|
s2 (t4-t3) |
2.4 ± 4.7 |
1.5 - 3.4 |
2.9 ± 5.0 |
2.4 -3.5 |
5.3 ± 8.9 |
4.1- 6.6 |
<0.0001 |
|
s3 (t8-t5) |
10.2 ± 8.7 |
8.4- 11.9 |
11.5 ± 10.2 |
10.4 -12.6 |
21.8 ± 19.1 |
18.9 - 24.8 |
<0.0001 |
|
t4int (t5-t4) |
12.0 ± 5.7 |
10.9-13.1 |
11.5 ± 6.5 |
10.8-12.2 |
8.7 ± 10.2 |
7.2-10.1 |
<0.0001 |
| t5-t2 | 24.9 ± 5.8 | 23.8-26.0 | 24.6 ± 7.8 | 23.8-25.4 | 21.9 ± 16.2 | 19.7-24.2 | <0.01 |
Embryos being cultured for blastocyst transfer cycles (n = 648) were divided into three groups: (A) BL-T, blastocysts transferred, (B) BL-F, blastocysts.
frozen and (C) PQ-D, Poor quality blastocysts/embryos failing to blastulate. Mean timings in BL-T and BL-F blastocysts(Group A, B) shown and compared to Group C. P value <0.05 was considered to be significant.