Table 1.
Characteristics | Control n = 29 | Recurrent pregnancy loss n = 21 | P value |
---|---|---|---|
Age (y) mean (SD) |
29.8 (4.1) |
33.9 (4.7) |
0.001a |
N. of miscarriage mean (SEM) |
|
3.5 (0.3) |
|
Endometrial dating |
|
|
|
in/out-of-phase (n) |
26/3 |
10/11 |
0.001b |
Defect type
c
n (%) |
|
|
|
In phase with β3 + |
24 (82.8) |
6 (28.6) |
0.0005b |
Type I |
3 (10.3) |
11 (52.4) |
|
Type II | 2 (6.9) | 4 (19.1) |
aUnpaired Student t test.
bChi-square for trend.
cIn phase endometrium has positive β3 integrin subunit.
Type I defect is an out-of-phase endometrium and β3 integrin subunit expression is negative.
Type II defect is an “in-phase” endometrium and β3 integrin subunit expression is negative.