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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: In Vivo. 2014 Mar-Apr;28(2):147–171.

Table VI.

Percentage of DNA promoter methylation for 6 representative genes in the lungs of 20 Gy thoracic irradiated C57BL/6NHsd mice.

day TGFb SOD2 FGF1 VEGFa CTGF IGFbp7
0 96.25±0.90
(n=4)		 92.65±1.18
(n=4)		 96.71±0.64
(n=4)		 95.10±0.77
(n=4)		 93.93±0.87
(n=4)		 95.23±0.73
(n=4)
2 98.88±0.40
(n=4)		 98.35±0.54
(n=4)		 98.81±0.36
(n=4)		 98.50±0.84
(n=4)		 99.40±0.29
(n=4)		 81.84±1.68
(n=4)
p=0.0018 p=0.0001 p=0.0013 p=0.0010 p<0.0001 p<0.0001
14 88.28±2.39
(n=4)		 89.53±4.07
(n=4)		 92.50±2.38
(n=4)		 98.78±0.30
(n=4)		 97.80±0.55
(n=4)		 81.75±1.50
(n=4)
p=0.0008 p=0.1908 p=0.0143 p=0.0001 p=0.0003 p<0.0001
28 84.45±3.39
(n=4)		 90.00±2.16
(n=4)		 91.40±2.33
(n=4)		 98.70±0.55
(n=4)		 97.53±0.49
(n=4)		 82.50±2.38
(n=4)
p=0.0005 p=0.0749 p=0.0046 p=0.0003 p=0.0004 p=0.0001
75 75.08±3.15
(n=4)		 80.75±3.30
(n=4)		 86.63±0.97
(n=4)		 99.00±0.26
(n=4)		 97.00±0.92
(n=4)		 83.96±1.89
(n=4)
p<0.0001 p=0.0005 p<0.0001 p=0.0001 p=0.0028 p<0.0001
100 76.45±1.63
(n=4)		 86.00±1.88
(n=4)		 88.08±2.26
(n=4)		 98.30±0.48
(n=4)		 98.00±0.64
(n=4)		 90.85±1.74
(n=4)
p<0.0001 p=0.0010 p=0.0003 p=0.0004 p=0.0003 p=0.0035
150 96.83±0.64
(n=4)		 97.40±0.72
(n=4)		 95.88±1.17
(n=4)		 98.98±0.51
(n=4)		 99.43±0.43
(n=4)		 97.78±1.34
(n=4)
p=0.3378 p=0.0005 p=0.2582 p=0.0002 p<0.0001 p=0.0156
200 98.20±0.55
(n=4)		 98.23±0.53
(n=4)		 96.38±0.87
(n=4)		 98.43±0.46
(n=4)		 99.08±0.33
(n=4)		 98.30±0.39
(n=4)
p=0.0101 p=0.0001 p=0.5603 p=0.0003 p<0.0001 p=0.0003

Data summary using mean±SD and group comparisons for methylation data, where p is the p-value for the comparison of DNA promoter methylation percentage for the corresponding gene in lungs of C57BL/6NHsd mice between each day and day 0, using the two-sided two sample t-test.