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. Author manuscript; available in PMC: 2014 Jun 30.
Published in final edited form as: J Nucl Med. 2014 Apr 3;55(5):805–811. doi: 10.2967/jnumed.113.134031

FIGURE 4.

FIGURE 4

Monitoring hepatic infection and transgene expression by imaging PSMA in a murine model. Athymic nude mice were intravenously administered adenovirus expressing PSMA or negative control gene (luciferase [Luc]). Seventy-two hours after injection of adenovirus, animals were imaged and specific uptake was observed in liver of animals by optical (A) and SPECT (B) imaging. SPECT images were obtained 15 min after injection of radiotracer, with similar levels of radioactivity in liver at 4 h after injection (Supplemental Fig. 4).