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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: J Bone Miner Res. 2014 May;29(5):1118–1130. doi: 10.1002/jbmr.2113

Figure 3.

Figure 3

Alterations in S6K1 and 4E-BP1 phosphorylation of (A) gastrocnemius and (B) quadriceps muscle obtained from mice subjected to normal loading (Control; Cont) or mechanical unloading via hindlimb suspension (Suspended; Susp). There was no significant difference in the total amount of total S6K1and 4E-BP1 between Control and Suspended muscle at any time point (data not shown). (Left) Representative Western blots of phosphorylated and total proteins of interest. Western blots for Control and Suspended muscle from the same time point were run on the same gel. (Right) Densitometric quantitation of all Western blot data. (n=9/group). Data shown as Mean ± SEM. * indicates a significant difference of Suspended from time-matched Control value (p<0.05).

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