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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: J Bone Miner Res. 2014 May;29(5):1118–1130. doi: 10.1002/jbmr.2113

Figure 4.

Figure 4

Cortical microstructural parameters obtained via microcomputed tomography scans of tibias and femurs obtained from mice subjected to normal loading conditions (Control) or mechanical unloading via hindlimb suspension (Suspended). Measured parameters at the tibia midshaft (A) included cortical thickness (Ct.Th), cortical area (Ct.Ar), total area (Tt.Ar), cortical area fraction (Ct.Ar/Tt.Ar), marrow area (Ma.Ar), cortical porosity (Ct.Po), cortical bone mineral density (BMD), polar moment of inertia (pMOI). Length of the tibia was also measured. These parameters were also determined for cortical bone at the femur midshaft (B). (n=12-16/group). Data shown as Mean ± SEM. Significant difference between two time points within a loading condition (Control or Suspended) is indicated as: † p<0.05 vs. Day 0, ∇p<0.05 vs. Day 7, Ω p<0.05 vs. Day 14, while * indicates a significant difference of Suspended from time-matched Control value (p<0.05).

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