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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: J Bone Miner Res. 2014 May;29(5):1118–1130. doi: 10.1002/jbmr.2113

Figure 5.

Figure 5

Trabecular microstructural parameters obtained via microcomputed tomography scans of tibias and femurs obtained from mice subjected to normal loading conditions (Control) or mechanical unloading via hindlimb suspension (Suspended). Measured parameters at the proximal tibia (A) included bone volume (BV), total volume (TV), bone volume fraction (BV/TV), trabecular thickness (Tb.Th), trabecular number (Tb.N), trabecular separation (Tb.Sp), connectivity density (Conn.D), structure model index (SMI), and tissue mineral density (TMD). These parameters were also determined for trabecular bone at the distal femur (B). (n=12-16/group). Data shown as Mean ± SEM. Significant difference between two time points within a loading condition (Control or Suspended) is indicated as: † p<0.05 vs. Day 0, ∇p<0.05 vs. Day 7, Ω p<0.05 vs. Day 14, while * indicates a significant difference of Suspended from time-matched Control value (p<0.05).

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