Figure 7.
Bone mechanical properties from mice subjected to normal loading conditions (Control) or mechanical unloading via hindlimb suspension (Suspended). Measured parameters of the tibia (A) included ultimate bending moment, stress, bending rigidity, ultimate bending energy, total bending energy, and ultimate normalized displacement (at maximum force). These parameters were also determined for the femur (B). (n=12-16/group). Data shown as Mean ± SEM. Significant difference between two time points within a loading condition (Control or Suspended) is indicated as: † p<0.05 vs. Day 0, ∇p<0.05 vs. Day 7, Ω p<0.05 vs. Day 14, while * indicates a significant difference of Suspended from time-matched Control value (p<0.05).