Table 2.

Association between IgG responses to PfRh5 and PfRipr and time-to-first clinical episode.

	PfRh5						PfRipr
	M vs L			H vs L			M vs L			H vs L
	HR	95% CI	P	HR	95% CI	P	HR	95% CI	P	HR	95% CI	P
Unadjusted	0.45	(0.26–0.77)	<0.01	0.17	(0.08–0.35)	<0.01	0.90	(0.51–1.60)	0.73	0.55	(0.30–1.00)	0.053
Adjusted	0.38	(0.22–0.68)	<0.01	0.18	(0.08–0.39)	<0.01	0.90	(0.50–1.61)	0.72	0.64	(0.35–1.17)	0.150

Hazard ratios (HRs) were determined to assess associations with anti-PhRh5 and anti-PfRipr antibody responses and time to P. falciparum clinical episodes with ≥5000 parasites/μl. Values represent unadjusted and adjusted ratios (age and location) ±95% confidence intervals (CI). Significant associations are shown in bold.